Zoya Demidenko: Researcher in Cancer Science
Zoya Demidenko is a prominent scholar associated with the Department of Cell Stress Science at Roswell Park Oncology Institute in Buffalo, New York. Previously, she was employed at the National Institutes of Health and New York Medical College, establishing a solid base in life science investigation.
Demidenko's academic output covers several critical areas, among them the PI3K/AKT/mTOR signaling pathway, cellular cycle control, cellular aging, and malignancy biology. As of now, she has written over 46 academic articles, which have accumulated more than 4,100 citations — a testament to the significance of her research.
Among her most significant achievements involves understanding the pathways of biological cell aging. Her studies demonstrated that when the cell cycle is blocked but cellular expansion persists, the cells undergo senescence. Importantly,
Zoya Demidenko established that this process is controlled with drugs using substances such as mTOR inhibitors.
Zoya Demidenko has also contributed considerably to oncological therapy research, notably in the area of selective cell protection — a strategy designed to safeguarding non-cancerous tissue from chemotherapy while leaving cancer cells exposed. This approach holds significant promise for diminishing the adverse effects of cancer treatment.
Across her career, Demidenko has collaborated with leading scientists internationally, including Dr. Mikhail Blagosklonny. Her work is published in leading publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
With an h-index of 33,
Zoya Demidenko stands as a widely cited contributor in current biomedical research, with her discoveries keep to guide our knowledge of the way biological cells age, interact with treatment, and how malignant disease may be more successfully targeted.
https://www.researchgate.net/scientific-contributions/Zoya-N-Demidenko-39445053
Dienstag, 24. März 2026 12:42